Peter Thiel, one of the few original minds in the life extension and accelerating-technological-change community, is featured in a short interview at Wired. Thiel seems to be aware of the limitations of extrapolation of trends:

We’ve been living in a unique period of accelerating technological progress. We’ve gone from horses to cars to planes to rockets to computers to the Internet in a very short time. It’s not automatic that that continues.

In a 2008 essay for the Hoover Institute, Thiel writes:

Thought experiments are notoriously misleading. Unlike more rigorous forms of scientific investigation, there are no empirical means to falsify these mental exercises. The optimistic thought experiment exists largely in the mind. The vistas of the mind are not always the same as reality. One could do worse than to ignore Milton ’s seductive promise: “The mind is its own place, and in itself, can make a heaven of hell, a hell of heaven.

As has been argued on this website before, the life extension movement suffers from an abundance of individuals who engage in thought experiments and organize conferences to talk to other people who engage in thought experiments.  But the fight against aging  cannot be won through speculation and wishful thinking alone but is in serious need of an “empirical turn”  that will unleash an avalanche of experimental research.

Further reading: 2008 Reason Interview with Peter Thiel