Under ideal circumstances cryonics patients are stabilized immediately after pronouncement of legal death by restoring blood flow to the brain, lowering temperature, and administering medications.
It has been shown that perfusability of the brain is significantly compromised after long-term (>5 min) ischemic events (the “no reflow” phenomenon). Improving cerebral blood
One concern about prolonged cardiopulmonary support in cryonics is that its decreasing effectiveness may not be able to meet cerebral oxygen demand, and may even become detrimental.